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About Geistlich Bio-Oss Collagen®

Geistlich Bio-Oss Collagen® combines the predictability of Geistlich Bio-Oss® with the addition of 10% collagen.

  • Promotes rapid vascularization and epithelial regeneration1
  • Encourages bone regeneration resulting in good soft tissue esthetics2,3
  • Achieves volume preservation due to slow resorption4,5
  • Improves pocket depth (PD) and clinical attachment level (CAL)6,7
  • Regenerates the complete periodontium7


Intentionally designed to stabilize the existing clot, yield faster bone regeneration and improve bone quality8

  • Collagen is a complex tissue important for cell growth, repair and regeneration.
  • Angiogenesis stimulates early vascularity with collagen pathways that provide vascular channels for tissue integration and bone formation.
  • Combined with Geistlich Bio-Oss®, the most trusted and proven xenogeneic bone substitute
  • Studies have shown less buccal dehiscences, increased horizontal bone volume, and improved soft-tissue healing when combining Geistlich Bio-Oss Collagen® + Geistlich Bio-Gide® vs DFDBA + a cross-linked membrane.9


The ability to adapt Geistlich Bio-Oss Collagen® to the specific defect allows for exceptional handling and ease of use

  • Addition of 10% porcine collagen enhances handling characteristics10,11
  • Tailor the material to the defect morphology
  • Trim to size and optimally placed for contour augmentation
  • Treat a wide range of bony defects

Handling Geistlich Bio-Oss Collagen®

Geistlich Bio-Oss Collagen®

“Geistlich Bio-Oss Collagen® 50 mg was the ideal size graft material for placement between the implant and facial plate for maintaining the hard and soft-tissue volume throughout the course of osseointegration and healing.”

– Dr. Justin Kang | Edgewater, New Jersey, USA

“Geistlich Bio-Oss Collagen® is easy to handle and allows bone grafting procedures to be predictable. The material can be easily trimmed, and manipulated to any defect. It’s collagen make up allows for blood clot stability with better adhesion to the treatment site. While I have used many bone grafting materials in the past 30 years, Geistlich Bio-Oss Collagen® continuously yields successful results. This product can be easily introduced and implemented into your daily practice.”

– Dr. Mario Vilardi | Fishkill, New York, USA

“I routinely rely on Geistlich Bio-Oss Collagen® in my practice — it’s very easy to shape and apply. It is an excellent material for space making defects. It has good hemostatic properties and stays where you place it.”

– Dr. Alan Meltzer | Voorhees, New Jersey, USA

“Geistlich Bio-Oss Collagen® is an excellent product. It has changed my implant practice.”

– Dr. Collin M. Stutz | Creve Coeur, Missouri, USA

“Geistlich Bio-Oss Collagen® is by far, the best and most predictable graft material I have ever used.”

– Dr. John Heldridge | Edmonds, Washington, USA

“Geistlich Bio-Oss Collagen® is the only graft material I use around immediate implants and helps me achieve incredible predictability and success.”

– Dr. Israel Puterman | Chevy Chase, Maryland, USA

“When hydrated and placed appropriately, Geistlich Bio-Oss Collagen® makes the procedure more efficient and predictable.”

– Dr. Leonard E. Schiffman | Woodmere, New York, USA

“Geistlich Bio-Oss Collagen® is the ONLY graft material I use for extraction sockets.”

– Dr. John Parnoff | New Haven, Connecticut, USA

Frequently Asked Questions

Is Geistlich Bio-Oss Collagen® a collagen plug?

No. Geistlich Bio-Oss Collagen® is a mixture of 90% Geistlich Bio-Oss® spongiosa granules and 10% highly purified porcine collagen in a block form. Geistlich Bio-Oss® is a natural bone mineral of bovine origin. The collagen facilitates adaptation of the Geistlich Bio-Oss® to the defect site.

Do I need a membrane when using Geistlich Bio-Oss Collagen® ?

The collagen in Geistlich Bio-Oss Collagen® does not function as a membrane. When space maintenance is required, it is recommended to use a membrane for optimal results1.

  1. Perelmann-Karmon, et al.:  Int J Periodontics Restorative Dent 2012; 32(4): 459-65.

What are the recommended indications for Geistlich Bio-Oss Collagen® ?

Geistlich Bio-Oss Collagen® is recommended for the reconstruction of bone defects in the following procedures:

  • Augmentation/reconstruction of alveolar ridges.
  • Filling of extraction sockets.
  • Preparation of implant sites, filling of bone dehiscences, and sinus floor augmentations.
  • Filling of periodontal bone defects, membrane support during guided bone regeneration (GBR) and guided tissue regeneration (GTR).

When can I use Geistlich Bio-Oss® and when Geistlich Bio-Oss Collagen® ?

Geistlich Bio-Oss® and Geistlich Bio-Oss Collagen® share the same indications. These products may be used interchangeably in the following procedures: 

  • Augmentation or reconstructive treatment of the alveolar ridge.
  • Filling of periodontal defects.
  • Filling of defects after root resection, apicoectomy, and cystectomy.
  • Filling of extraction sockets to enhance preservation of the alveolar ridge.
  • Elevation of the maxillary sinus floor.
  • Filling of periodontal defects in conjunction with products intended for Guided Tissue Regeneration(GTR) and Guided Bone Regeneration (GBR).
  • Filling of peri-implant defects in conjunction with products intended for Guided Bone Regeneration (GBR).

Is it possible to have an allergic reaction to Geistlich Bio-Oss Collagen® ?

As Geistlich Bio-Oss Collagen® contains collagen, allergic and inflammatory tissue reactions cannot be excluded. These are, however, extremely rare.

  1. Pawelec KM, Best SM, Cameron RE. (2016) Collagen: a network for regenerative medicine. J Mater Chem B 2016;4(40):6484-6496.
  2. Jung RE et al., Int J Periodontics Restorative Dent 2004;24:545-553.
  3. Jung RE, et al.: J Clin Periodontol 2013, Jan; 40(1): 90-98.
  4. Araujo MG, et al.: Clin Oral Implants Res 2010; 21(1): 55-64.
  5. Mordenfeld AT, et al.: Clin Implant Dent Relat Res 2012, Oct 15 (Epub ahead of print).
  6. Sculean A, et al.: J Clin Periodontol 2005: 32(7): 720-24.
  7. Nevins ML, et al.: Int J Periodontics Restorative Dent 2003; 23(1): 9-17.
  8. Doillon CJ, Silver FH. Collagen-based wound dressing: Effects of hyaluronic acid and fibronectin on wound healing. Biomaterials 1986;7(1): 3-8.
  9. Scheyer et al. 2016
  10. Trevisiol L, et al.: J Craniofac Surg 2012, 23(5): 1343-48. 
  11. Rohner D, et al.: Int J Oral Maxillofac Surg 2013; 42(5): 585-91.